RFD4-Proteina

WebGPU FP16

Designs can run about 2× faster with Chrome's experimental WebGPU features. Paste chrome://flags/#enable-unsafe-webgpu into the address bar, set it to Enabled and relaunch Chrome. It applies to every site, not just this one.

What do you want to design?

Or start from your own structure

Task

Contig

Designs

Thinking none low med high

Seed

More settings

Lower K = higher temperature and more variation. Defaults give stronger low-temperature sampling.

Backbone K Latents (sequence) K Partial diffusion Partial diffusion (% of trajectory) Early stop when converged

View

Refold with

AlphaFold 3 model parameters

These are Google DeepMind's parameters. They are not available for commercial use and carry a prohibited-use policy.

OpenBind-0 runs the same architecture under Apache 2.0. It is a different model.

AlphaFold 3 weights terms · prohibited use policy

Advanced editor

AtomWorks Studio

No structure open

Open CIF

Import options

Parse settings

Assembly

Combine CIF

Error

Style

No atoms have coordinates to display.

Target

Representation Show Hide Show only

Analyze

Interactions H-bonds Hydrophobic π-stacking π-cation Salt bridges Halogen Metal

H-bond model Scope

Inter-chain only Visualize dashed contacts Maximum visualized contacts

Measurement

Backend

Renderer

Patinae command catalog

Choose renderer

Pick 0 atoms selected Click to add · Click again to remove

Sequence Click to toggle · Drag · Shift range

Open a structure to select residues.

Choose a renderer

Open the Studio with Patinae or Mol*

Both use the same annotations and editing tools.

No 3D coordinates to display

This input contains only unpositioned atoms or expandable segments. Its sequence, bonds, and conditions remain editable.

Style controls need positioned atoms. Load a structure with coordinates to see it here.

What do you want to design?

Start from a worked example, or open your own structure.

Backbone · view only

Examples

Annotated design inputs. Loading an example opens a new document.

Structure

Open an annotated CIF to begin.

Open a structure to begin.

Annotations

Type Enable condition

Select one or more atoms.

Conditions on this structure

Click a condition to highlight it and see its values. Click again to restore the previous colors. This only changes the view.

Open a structure to see its conditions.

Choose a condition above, or click an atom to see its conditions.

Charges

Charge action Charge

Protonation

Updates hydrogens and formal charges for the whole structure. Undo restores the previous state.

Bonds

Select exactly two atoms to add or remove a bond.

Bond type

Inspect bonds touching the selected atoms.

Structure editing

Close residue-ID gaps after delete

Expandable segments

Min Max

Insert before selection Create as a new chain

Chain ID Chain type

Select atoms or residues to insert before the first selected residue, or after the last when unchecked. A new chain needs no selection.

Objects

Open a structure to list objects.

Selections

0 atoms in active selection

Measurements

No measurements.

Interactions

Activity log

Starting Studio…

Starting Studio… Guide